Immunohistochemical Detection of EGFR Mutation Using Mutation-Specific Antibodies in Lung Cancer
نویسندگان
چکیده
منابع مشابه
Immunohistochemical detection of EGFR mutation using mutation-specific antibodies in lung cancer.
PURPOSE Patients with mutations of epidermal growth factor receptor (EGFR) receive more benefit from EGFR-tyrosine kinase inhibitor treatment. However, usually such treatment is used to treat advanced lung cancer and only small biopsy samples are available for mutational analysis. We used immunohistochemistry to examine recently developed antibodies specific to major hotspot mutations of L858R ...
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2010
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-10-0129